Studies on Outer Membrane Proteins of Moraxella nonliquefaciens

Selective medium for Moraxella nonliquefaciens.

A medium is described which selectively inhibits most bacteria from the normal flora of the conjunctiva, the lid-margin, and the upper respiratory tract but permits growth of Moraxella nonliquefaciens, M. liquefaciens, and the less fastidious strains of M. lacunata. The selective conditions are obtained with thiostrepton, tyrothricin, and sodium nalidixinate as inhibitors. Incubation under incr...

Posttrabeculectomy endophthalmitis caused by Moraxella nonliquefaciens.

Moraxella nonliquefaciens, a commensal organism of the upper respiratory tract, is generally considered to have low pathogenic potential. We report here two cases of severe endophthalmitis occurring 9 years and 2 months after glaucoma filtration surgery, respectively. Apart from sulfonamide, very low MICs were recorded for several antibiotics tested. Identification was based on phenotypic chara...

Rapid typing of Moraxella catarrhalis subpopulations based on outer membrane proteins using mass spectrometry.

Moraxella catarrhalis is a major mucosal pathogen of the human respiratory tract both in children and in adults. Two subpopulations of this organism have been described that differ in 16S rRNA gene sequence and virulence traits. Three 16S rRNA types have been defined. 2-DE followed by protein identification by MS revealed significant differences in the outer membrane protein (OMP) patterns of e...

Salivary antibodies directed against outer membrane proteins of Moraxella catarrhalis in healthy adults.

Moraxella catarrhalis is a major mucosal pathogen of the human respiratory tract, but the mucosal immune response directed against surface components of this organism has not been characterized in detail. The aim of this study was to investigate the salivary immunoglobulin A (IgA) response toward outer membrane proteins (OMP) of M. catarrhalis in healthy adults, the group of individuals least l...

The outer membrane protein OlpA contributes to Moraxella catarrhalis serum